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NICE proposes to withdraw Alzheimer's drugs from NHS
Nieuws van: BMJ
The drugs donepezil, rivastigmine, galantamine, and memantine should no longer be prescribed on the NHS to treat Alzheimer's disease, says new draft guidance from the National Institute for Clinical Excellence (NICE).
NICE, the NHS prescribing watchdog for England and Wales, has retracted its previous guidance "issued in 2001 and which said that these drugs should be prescribed for Alzheimer's disease—after reviewing the latest evidence on efficacy and cost effectiveness. Patients currently receiving any of the drugs, however, can continue to do so. Memantine will be available only as part of a clinical trial with strict outcome criteria.
Comments on the proposals are being accepted until 21 March, and final guidance is expected to come into force in July this year.
The NICE assessment group says that, although donepezil, rivastigmine, and galantamine (collectively known as anticholinesterase inhibitors) have proved gains in cognitive and global scales compared with placebo in people with mild . .
http://bmj.bmjjournals.com/cgi/content/extract/330/7490/495-a - 4 Mar 2005
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